Topic
Degradants
Page 6 of 13 — Deamidation at plus one dalton, oxidation at plus sixteen, truncation sequences, and what a warm transit actually does.
Messages — page 6 of 13
travel_coolerplus 0.98 is deamidation#hplc-massspec · 2025-11-13fasting_insulinplus 16 is oxidation#hplc-massspec · 2025-11-13area_percentoxidation is about plus 15.99 Da and is usually methionine or tryptophan#hplc-massspec · 2025-11-15HPLC_Hankplus sixteen, is that always oxidation#hplc-massspec · 2025-11-15batch_banditdeamidation is about plus 0.98 Da. it is not a rounding error, it is a degradant#hplc-massspec · 2025-11-15batch_banditplus 0.98 is deamidation#hplc-massspec · 2025-11-15declared_valueplus sixteen, is that always oxidation#hplc-massspec · 2025-11-16eat_more_pleasedeamidation is about plus 0.98 Da. it is not a rounding error, it is a degradant#hplc-massspec · 2025-11-16verify_or_dontoxidation is about plus 15.99 Da and is usually methionine or tryptophan#hplc-massspec · 2025-11-16vialkeeperplus 0.98 is deamidation#hplc-massspec · 2025-11-16vialkeeperplus 16 is oxidation#hplc-massspec · 2025-11-16provincial_pattruncations show as a mass deficit matching one or more residues. you need the sequence to say which#hplc-massspec · 2025-11-16salt_bridgeplus 0.98 is deamidation#hplc-massspec · 2025-11-19area_percentplus 16 is oxidation#hplc-massspec · 2025-11-19thirty_min_waitdeamidation is about plus 0.98 Da. it is not a rounding error, it is a degradant, happy to be corrected#hplc-massspec · 2025-11-19gradient_greghow would a truncation sequence show up#hplc-massspec · 2025-11-21underfill_umatruncations show as a mass deficit matching one or more residues. you need the sequence to say which#hplc-massspec · 2025-11-21gradient_gregplus sixteen, is that always oxidation#hplc-massspec · 2025-11-21ms_ms_miraa warm transit can put a visible degradant peak on a chromatogram. that is what 20 days at ambient does#hplc-massspec · 2025-11-24charge_stateplus sixteen, is that always oxidation#hplc-massspec · 2025-11-24area_percenttruncations show as a mass deficit matching one or more residues. you need the sequence to say which#hplc-massspec · 2025-11-24monoisotopichow would a truncation sequence show up#hplc-massspec · 2025-11-24HPLC_Hankplus 0.98 is deamidation#hplc-massspec · 2025-11-24fridge_thermoplus 16 is oxidation#hplc-massspec · 2025-11-29fridge_thermoplus 0.98 is deamidation#hplc-massspec · 2025-11-29deamidationa warm transit can put a visible degradant peak on a chromatogram. that is what 11 days at ambient does#hplc-massspec · 2025-11-29coa_or_copeplus 0.98 is deamidation#hplc-massspec · 2025-12-01coa_or_copedeamidation is about plus 0.98 Da. it is not a rounding error, it is a degradant, ask me again in a month#hplc-massspec · 2025-12-01courier_vs_posta warm transit can put a visible degradant peak on a chromatogram. that is what 15 days at ambient does#hplc-massspec · 2025-12-01still_here_2024plus 16 is oxidation#hplc-massspec · 2025-12-01no_chargebacktruncations show as a mass deficit matching one or more residues. you need the sequence to say which#hplc-massspec · 2025-12-01HPLC_Hankwhile im here a warm transit can put a visible degradant peak on a chromatogram. that is what 11 days at ambient does#hplc-massspec · 2025-12-03two_ml_twoplus sixteen, is that always oxidation#hplc-massspec · 2025-12-03fasting_insulinhow would a truncation sequence show up#hplc-massspec · 2025-12-03bengaluru_bacfor the archive how would a truncation sequence show up#hplc-massspec · 2025-12-04area_percentplus sixteen, is that always oxidation#hplc-massspec · 2025-12-04stable_not_volatileoxidation is about plus 15.99 Da and is usually methionine or tryptophan#hplc-massspec · 2025-12-04area_percenta warm transit can put a visible degradant peak on a chromatogram. that is what 26 days at ambient does#hplc-massspec · 2025-12-04acetate_ashplus sixteen, is that always oxidation#hplc-massspec · 2025-12-08quill_questionstruncations show as a mass deficit matching one or more residues. you need the sequence to say which#hplc-massspec · 2025-12-08monoisotopichow would a truncation sequence show up#hplc-massspec · 2025-12-08mg_per_mloxidation is about plus 15.99 Da and is usually methionine or tryptophan#hplc-massspec · 2025-12-11tail_factorplus sixteen, is that always oxidation#hplc-massspec · 2025-12-11surpass_twoplus 0.98 is deamidation#hplc-massspec · 2025-12-11mg_per_mlhow would a truncation sequence show up#hplc-massspec · 2025-12-11unsolicited_dmplus 0.98 is deamidation#hplc-massspec · 2025-12-12snac_and_waterupdate on the earlier thing deamidation is about plus 0.98 Da. it is not a rounding error, it is a degradant#hplc-massspec · 2025-12-13snac_and_waterplus 0.98 is deamidation#hplc-massspec · 2025-12-13monoisotopica C18 column separates by hydrophobicity under your gradient. anything with similar hydrophobicity comes off at a similar…#hplc-massspec · 2025-12-17igf_one_ivyplus 0.98 is deamidation#hplc-massspec · 2025-12-18assay_not_puritydeamidation is about plus 0.98 Da. it is not a rounding error, it is a degradant#hplc-massspec · 2025-12-18yara_yieldsplus sixteen, is that always oxidation#hplc-massspec · 2025-12-18ferrous_ashplus sixteen, is that always oxidation#hplc-massspec · 2025-12-19ferrous_ashslightly off topic but how would a truncation sequence show up#hplc-massspec · 2025-12-19closer_not_simplertruncations show as a mass deficit matching one or more residues. you need the sequence to say which#hplc-massspec · 2025-12-20closer_not_simplerplus 16 is oxidation#hplc-massspec · 2025-12-20sharps_comedyplus 16 is oxidation#hplc-massspec · 2026-01-03tokyo_tapera warm transit can put a visible degradant peak on a chromatogram. that is what 16 days at ambient does#hplc-massspec · 2026-01-03LC_MS_Lenaright so truncations show as a mass deficit matching one or more residues. you need the sequence to say which#hplc-massspec · 2026-01-03tokyo_taperhow would a truncation sequence show up#hplc-massspec · 2026-01-03