Topic
Degradants
Page 3 of 13 — Deamidation at plus one dalton, oxidation at plus sixteen, truncation sequences, and what a warm transit actually does.
Messages — page 3 of 13
vat_on_importplus 0.98 is deamidation#hplc-massspec · 2025-05-25vat_on_importhow would a truncation sequence show up#hplc-massspec · 2025-05-25septum_salplus 16 is oxidation#hplc-massspec · 2025-05-25VialBotArchive lookup: deamidation first appears in this channel on 2024-11-08.#test-results · 2025-05-30identity_shiftplus 0.98 is deamidation#hplc-massspec · 2025-06-05maintenance_moslightly off topic but oxidation is about plus 15.99 Da and is usually methionine or tryptophan#hplc-massspec · 2025-06-05provincial_pathow would a truncation sequence show up#hplc-massspec · 2025-06-05provincial_pata warm transit can put a visible degradant peak on a chromatogram. that is what 12 days at ambient does#hplc-massspec · 2025-06-05identity_shiftdeamidation is about plus 0.98 Da. it is not a rounding error, it is a degradant#hplc-massspec · 2025-06-05maintenance_moplus sixteen, is that always oxidation#hplc-massspec · 2025-06-05swab_dry_firstdeamidation is about plus 0.98 Da. it is not a rounding error, it is a degradant#hplc-massspec · 2025-06-08LC_MS_Lenaa warm transit can put a visible degradant peak on a chromatogram. that is what 12 days at ambient does#hplc-massspec · 2025-06-08swab_dry_firsthow would a truncation sequence show up#hplc-massspec · 2025-06-08swab_dry_firstfor the archive oxidation is about plus 15.99 Da and is usually methionine or tryptophan, happy to be corrected#hplc-massspec · 2025-06-08egfr_edplus sixteen, is that always oxidation#hplc-massspec · 2025-06-11acetate_ashfollow up how would a truncation sequence show up a dimer usually shows up late and at roughly double the mass. the…#hplc-massspec · 2025-06-11assay_not_purityplus sixteen, is that always oxidation#hplc-massspec · 2025-06-12assay_not_purityplus 16 is oxidation#hplc-massspec · 2025-06-12assay_not_purityplus 0.98 is deamidation#hplc-massspec · 2025-06-12monoisotopictruncations show as a mass deficit matching one or more residues. you need the sequence to say which, n of 1 obviously#hplc-massspec · 2025-06-12seizure_lettertruncations show as a mass deficit matching one or more residues. you need the sequence to say which#hplc-massspec · 2025-06-14seizure_letterdeamidation is about plus 0.98 Da. it is not a rounding error, it is a degradant#hplc-massspec · 2025-06-14assay_not_purityplus 0.98 is deamidation#hplc-massspec · 2025-06-14truncation_truoxidation is about plus 15.99 Da and is usually methionine or tryptophan#hplc-massspec · 2025-06-14HPLC_Hankgenuine question a warm transit can put a visible degradant peak on a chromatogram. that is what 14 days at ambient does#hplc-massspec · 2025-06-14HPLC_Hankplus 16 is oxidation#hplc-massspec · 2025-06-14eight_mmplus 0.98 is deamidation#hplc-massspec · 2025-06-16panel_before_aftertruncations show as a mass deficit matching one or more residues. you need the sequence to say which#hplc-massspec · 2025-06-16truncation_trufor the archive deamidation is about plus 0.98 Da. it is not a rounding error, it is a degradant#hplc-massspec · 2025-06-19truncation_truoxidation is about plus 15.99 Da and is usually methionine or tryptophan truncations show as a mass deficit matching one or…#hplc-massspec · 2025-06-19void_volumeplus 16 is oxidation#hplc-massspec · 2025-06-19plateau_penoxidation is about plus 15.99 Da and is usually methionine or tryptophan#hplc-massspec · 2025-06-20plateau_penplus 16 is oxidation#hplc-massspec · 2025-06-20never_for_salesorry to jump in plus sixteen, is that always oxidation#hplc-massspec · 2025-06-20void_volumeplus 0.98 is deamidation#hplc-massspec · 2025-06-20patent_2026a warm transit can put a visible degradant peak on a chromatogram. that is what 22 days at ambient does#hplc-massspec · 2025-06-20third_shiftfollow up oxidation is about plus 15.99 Da and is usually methionine or tryptophan#hplc-massspec · 2025-06-21third_shifta warm transit can put a visible degradant peak on a chromatogram. that is what 12 days at ambient does, for what its worth#hplc-massspec · 2025-06-21mcg_not_mgwhile im here plus sixteen, is that always oxidation#hplc-massspec · 2025-06-21no_chargebackplus 0.98 is deamidation#hplc-massspec · 2025-06-22no_chargebackplus 16 is oxidation#hplc-massspec · 2025-06-22ferritin_faya warm transit can put a visible degradant peak on a chromatogram. that is what 11 days at ambient does, your mileage will…#hplc-massspec · 2025-06-22vial_ledgerplus 0.98 is deamidation#hplc-massspec · 2025-06-26retention_timehow would a truncation sequence show up#hplc-massspec · 2025-06-26vial_ledgersorry to jump in oxidation is about plus 15.99 Da and is usually methionine or tryptophan#hplc-massspec · 2025-06-26triple_ag_tomdeamidation is about plus 0.98 Da. it is not a rounding error, it is a degradant#hplc-massspec · 2025-07-05retention_timeplus 16 is oxidation#hplc-massspec · 2025-07-05nine_nine_onegenuine question plus sixteen, is that always oxidation#hplc-massspec · 2025-07-05hiccup_hollisunrelated but how would a truncation sequence show up#hplc-massspec · 2025-07-05gradient_gregplus 0.98 is deamidation#hplc-massspec · 2025-07-05area_percentso either the table is truncated or the numbers were typed by someone who was not reading them#coa-reading · 2025-07-06ms_ms_miraa warm transit can put a visible degradant peak on a chromatogram. that is what 12 days at ambient does#hplc-massspec · 2025-07-06hk_hplchow would a truncation sequence show up#hplc-massspec · 2025-07-08peak_splitplus 0.98 is deamidation#hplc-massspec · 2025-07-08LC_MS_Lenaplus 16 is oxidation#hplc-massspec · 2025-07-08tarpit_tamquick one deamidation is about plus 0.98 Da. it is not a rounding error, it is a degradant#hplc-massspec · 2025-07-08void_volumeplus 16 is oxidation#hplc-massspec · 2025-07-13tenpenceupdate on the earlier thing plus sixteen, is that always oxidation#hplc-massspec · 2025-07-15nausea_windowtruncations show as a mass deficit matching one or more residues. you need the sequence to say which#hplc-massspec · 2025-07-19cricket_or_footydeamidation is about plus 0.98 Da. it is not a rounding error, it is a degradant#hplc-massspec · 2025-07-19