Topic
Tirzepatide
Page 5 of 15 — Dual GIP/GLP-1 agonism, the SURMOUNT and SURPASS trials, the 2.5 to 15mg ladder, and the argument about whether anyone needs the…
Messages — page 5 of 15
hair_month_fourGI was about the same as tirzepatide for me, the difference was how fast it arrived#retatrutide · 2025-04-27third_shiftok so did the phase 2 result actually come in higher than the tirzepatide numbers#retatrutide · 2025-04-27sharps_comedywhats the plateau pattern here, same as semaglutide or different#tirzepatide · 2025-04-30dublin_doseeasier gi for me#tirzepatide · 2025-05-04area_percenttirzepatide is about 4813.5 Da, so 2+ is near 2407.8 and 3+ near 1605.5 the honest position is that hobby-level interpretation…#hplc-massspec · 2025-05-04blank_runappetite suppression at 2 was stronger than my tirzepatide experience at a comparable point my resting rate went up 2 bpm in…#retatrutide · 2025-05-06cold_chain_cmdrfor the archive the trials titrated every four weeks to a target, most people here stop at whatever works#tirzepatide · 2025-05-07group_buy_gwenGI was about the same as tirzepatide for me, the difference was how fast it arrived#retatrutide · 2025-05-10customs_owlis the GI worse than tirzepatide or about the same#retatrutide · 2025-05-10pinch_not_stretchthe trials escalated on a fixed schedule because a trial has to. you are not a trial#dosing-titration · 2025-05-13hot_mailboxGI was about the same as tirzepatide for me, the difference was how fast it arrived#retatrutide · 2025-05-14hot_mailboxappetite suppression at 0.25 was stronger than my tirzepatide experience at a comparable point#retatrutide · 2025-05-14snac_and_waterif SURPASS-2 already settled tirz vs sema why do people still argue#tirzepatide · 2025-05-19lean_mass_lexthe A1c results were genuinely striking though. all three tirz arms beat sema 1mg and a big fraction got under 5.7#tirzepatide · 2025-05-19lean_mass_lexcloser, and tirz still ahead on the mean in the direct comparison programme#tirzepatide · 2025-05-19lean_mass_lexside branch because we always end up here. the mechanism argument for why tirz is often easier on the stomach#tirzepatide · 2025-05-19step_one_sianappetite suppression at 12 was stronger than my tirzepatide experience at a comparable point#retatrutide · 2025-05-23triumph_watchlow and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom#retatrutide · 2025-05-23fridge_thermoappetite suppression at 0.5 was stronger than my tirzepatide experience at a comparable point#retatrutide · 2025-05-24relabel_watchlow and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom#retatrutide · 2025-05-24two_three_liftsfor the archive low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom#retatrutide · 2025-05-25amsterdam_aliquottirzepatide is about 4813.5 Da, so 2+ is near 2407.8 and 3+ near 1605.5#hplc-massspec · 2025-05-25salt_bridgepurely a supplier question. the compounds themselves have real published evidence behind them and that evidence says nothing…#vendor-talk · 2025-05-25gip_glp_gili argued the sweet spot was nonsense and then spent 11 months at 7.5 not needing more#tirzepatide · 2025-05-26area_percentGI was about the same as tirzepatide for me, the difference was how fast it arrived#retatrutide · 2025-05-28unsolicited_dmappetite suppression at 12 was stronger than my tirzepatide experience at a comparable point#retatrutide · 2025-05-28septum_sali jumped a rung once to catch up after a supply gap and it was a bad week. would not repeat#dosing-titration · 2025-05-28plateau_penquick one appetite suppression at 2.4 was stronger than my tirzepatide experience at a comparable point#retatrutide · 2025-05-30triple_ag_tomlow and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom#retatrutide · 2025-05-30reship_ritalow and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom#retatrutide · 2025-05-31endotoxin_edGI was about the same as tirzepatide for me, the difference was how fast it arrived#retatrutide · 2025-05-31two_ml_twoSURMOUNT is weight#tirzepatide · 2025-06-01still_here_2024update on the earlier thing appetite suppression at 1 was stronger than my tirzepatide experience at a comparable point#retatrutide · 2025-06-01reship_ritaGI was about the same as tirzepatide for me, the difference was how fast it arrived#retatrutide · 2025-06-01maintenance_molow and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom#retatrutide · 2025-06-02cat_on_the_traythats normal#bloodwork · 2025-06-02taper_tesswell done#wins · 2025-06-02belfast_bacGI was about the same as tirzepatide for me, the difference was how fast it arrived#retatrutide · 2025-06-03auckland_aliquotcoming off semaglutide, is there a conversion or do i restart at 2.5 i argued the sweet spot was nonsense and then spent 15…#tirzepatide · 2025-06-06area_percentslightly off topic but low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom#retatrutide · 2025-06-06fibre_firstappetite suppression at 0.5 was stronger than my tirzepatide experience at a comparable point#retatrutide · 2025-06-07third_shiftdid the phase 2 result actually come in higher than the tirzepatide numbers#retatrutide · 2025-06-07swab_dry_firsttirzepatide is about 4813.5 Da, so 2+ is near 2407.8 and 3+ near 1605.5#hplc-massspec · 2025-06-08triumph_watchfollow up is the GI worse than tirzepatide or about the same#retatrutide · 2025-06-09lot_number_loulow and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom#retatrutide · 2025-06-09salt_bridgefor the base rate question — in the head to head trial, adjudicated pancreatitis was rare on both drugs#bloodwork · 2025-06-10tarpit_tamis the GI worse than tirzepatide or about the same#retatrutide · 2025-06-11retention_timeappetite suppression at 12 was stronger than my tirzepatide experience at a comparable point#retatrutide · 2025-06-12step_one_sianlow and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom#retatrutide · 2025-06-12split_shipmentdid the phase 2 result actually come in higher than the tirzepatide numbers#retatrutide · 2025-06-13food_noise_offi log kilos because i think in kilos and put pounds in brackets so nobody has to convert anything#wins · 2025-06-13appetite_backis the GI worse than tirzepatide or about the same#retatrutide · 2025-06-14triple_ag_tomtirzepatide is about 4813.5 Da, so 2+ is near 2407.8 and 3+ near 1605.5#hplc-massspec · 2025-06-14marrow.modappetite suppression at 12 was stronger than my tirzepatide experience at a comparable point#retatrutide · 2025-06-15bea_reconstitutescame down from a treatment dose to maintenance over about three months and it was uneventful#dosing-titration · 2025-06-16eighteen_monthsthe honest answer to is this forever is that nobody knows and the drug only works while you are taking it#maintenance · 2025-06-17underfill_umalow and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom#retatrutide · 2025-06-18patent_2026tirzepatide is about 4813.5 Da, so 2+ is near 2407.8 and 3+ near 1605.5#hplc-massspec · 2025-06-20swab_dry_firstis the GI worse than tirzepatide or about the same#retatrutide · 2025-06-21orfor_watchslightly off topic but appetite suppression at 5 was stronger than my tirzepatide experience at a comparable point#retatrutide · 2025-06-22