Topic
Tirzepatide
Page 7 of 15 — Dual GIP/GLP-1 agonism, the SURMOUNT and SURPASS trials, the 2.5 to 15mg ladder, and the argument about whether anyone needs the…
Messages — page 7 of 15
cold_chain_cmdrlow and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom#retatrutide · 2025-08-07provincial_patappetite suppression at 12 was stronger than my tirzepatide experience at a comparable point#retatrutide · 2025-08-07verify_or_dontheld 10 for 15 months and lost 10kg over that stretch, slow and boring and fine#tirzepatide · 2025-08-08chain_of_custodylow and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom#retatrutide · 2025-08-08protein_floori stopped weighing daily at about month six and my mood improved more than my numbers did#wins · 2025-08-09lot_number_louanyone stopped at 10 and stayed there for months#tirzepatide · 2025-08-10tokyo_tapersorry to jump in plateau versus set point is not answerable in under six months of data#dosing-titration · 2025-08-10ghk_giathe sweet spot thing is survivorship, the people it worked for stayed and said so#tirzepatide · 2025-08-11cricket_or_footyappetite suppression at 10 was stronger than my tirzepatide experience at a comparable point#retatrutide · 2025-08-11low_and_slowslightly off topic but GI was about the same as tirzepatide for me, the difference was how fast it arrived#retatrutide · 2025-08-13rae_labelsis the GI worse than tirzepatide or about the same#retatrutide · 2025-08-14luerloklow and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom#retatrutide · 2025-08-16rory_reshipsappetite suppression at 2 was stronger than my tirzepatide experience at a comparable point#retatrutide · 2025-08-16aliquot_adais the GI worse than tirzepatide or about the same#retatrutide · 2025-08-16identity_shiftGI was about the same as tirzepatide for me, the difference was how fast it arrived#retatrutide · 2025-08-16swirl_not_shakedoes the appetite effect feel different or just stronger#tirzepatide · 2025-08-17two_ml_twotirzepatide is about 4813.5 Da, so 2+ is near 2407.8 and 3+ near 1605.5#hplc-massspec · 2025-08-17nine_nine_oneeasier gi for me#tirzepatide · 2025-08-19split_shipmentupdate on the earlier thing GI was noticeably easier for me than semaglutide at what felt like the same appetite effect#tirzepatide · 2025-08-19amsterdam_aliquotGI was about the same as tirzepatide for me, the difference was how fast it arrived#retatrutide · 2025-08-21mcg_not_mghow do you celebrate this without it being about food i log kilos because i think in kilos and put pounds in brackets so…#wins · 2025-08-22bea_reconstitutesslightly off topic but is the GI worse than tirzepatide or about the same#retatrutide · 2025-08-23bea_reconstitutesdid the phase 2 result actually come in higher than the tirzepatide numbers#retatrutide · 2025-08-23lyophile_livappetite suppression at 7.5 was stronger than my tirzepatide experience at a comparable point#retatrutide · 2025-08-23two_four_ceilingtirzepatide is about 4813.5 Da, so 2+ is near 2407.8 and 3+ near 1605.5#hplc-massspec · 2025-08-23triple_ag_tomGI was about the same as tirzepatide for me, the difference was how fast it arrived#retatrutide · 2025-08-24net_peptidelow and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom#retatrutide · 2025-08-24triumph_watchlow and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom, ill dig out the number#retatrutide · 2025-08-25split_shipmentis the GI worse than tirzepatide or about the same#retatrutide · 2025-08-26alt_ast_aliok so did the phase 2 result actually come in higher than the tirzepatide numbers#retatrutide · 2025-08-27patent_2026appetite suppression at 2.5 was stronger than my tirzepatide experience at a comparable point#retatrutide · 2025-08-29ms_ms_mirawhat would make you stop and go and see somebody rather than post here#bloodwork · 2025-08-29impersonator_ipGI was about the same as tirzepatide for me, the difference was how fast it arrived#retatrutide · 2025-08-30kev_measuresappetite suppression at 2.4 was stronger than my tirzepatide experience at a comparable point#retatrutide · 2025-08-31hard_stop_halGI was about the same as tirzepatide for me, the difference was how fast it arrived#retatrutide · 2025-08-31void_volume5 did nothing#tirzepatide · 2025-09-03area_percentGIP plus GLP-1#tirzepatide · 2025-09-05salt_bridgedid the phase 2 result actually come in higher than the tirzepatide numbers#retatrutide · 2025-09-05coa_or_copethe 15 vial in 2.5ml gives 4mg/ml which puts 1 on 20 units, nice round numbers#tirzepatide · 2025-09-06swab_dry_firstthe 15 vial in 1ml gives 5mg/ml which puts 1 on 30 units, nice round numbers#tirzepatide · 2025-09-08customs_owlim at 0.25 and thinking about 2.5, did anyone gain anything from that step#tirzepatide · 2025-09-08forty_five_kgthe trials titrated every four weeks to a target, most people here stop at whatever works GI was noticeably easier for me than…#tirzepatide · 2025-09-08bengaluru_bacis the GI worse than tirzepatide or about the same#retatrutide · 2025-09-09bengaluru_baclow and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom#retatrutide · 2025-09-09taste_changedappetite suppression at 2 was stronger than my tirzepatide experience at a comparable point#retatrutide · 2025-09-10appetite_backGI was about the same as tirzepatide for me, the difference was how fast it arrived#retatrutide · 2025-09-10rezept_rolfthe two compounds arent interchangeable week for week even if the effect ends up similar#tirzepatide · 2025-09-12cat_on_the_traycoming back to this tirzepatide is about 4813.5 Da, so 2+ is near 2407.8 and 3+ near 1605.5#hplc-massspec · 2025-09-12juno_joinsdid anyone drop the dose for maintenance or just stay where they were#maintenance · 2025-09-12meniscus_meltirzepatide is about 4813.5 Da, so 2+ is near 2407.8 and 3+ near 1605.5, i have it written down somewhere oxidation is about…#hplc-massspec · 2025-09-14reading_the_pinswhats the standard tirz ladder. i keep seeing different versions#tirzepatide · 2025-09-16dexa_or_biaring fitting is the best one#wins · 2025-09-16karl_fischerthe two compounds arent interchangeable week for week even if the effect ends up similar#tirzepatide · 2025-09-18gus_chartsdid the phase 2 result actually come in higher than the tirzepatide numbers#retatrutide · 2025-09-19cold_chain_cmdrSURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up#tirzepatide · 2025-09-20ghent_gradientdid the phase 2 result actually come in higher than the tirzepatide numbers#retatrutide · 2025-09-20taper_tessgenuine question blood pressure was 148 over 94 at baseline and 126 over 80 today, is that the weight or coincidence#wins · 2025-09-21coa_or_copethats not showing off#wins · 2025-09-22assay_not_purityis there a reason to titrate slower than the four week schedule#tirzepatide · 2025-09-25factory_direct_fiGI was about the same as tirzepatide for me, the difference was how fast it arrived#retatrutide · 2025-09-25