Topic
Retatrutide
Page 3 of 3 — Triple GIP/GLP-1/glucagon agonism, the Phase 2 result, the resting heart rate signal, and the room’s standing position that…
Messages — page 3 of 3
triple_ag_tomappetite returning at the end of the week is extremely common and is not the dose failing#dosing-titration · 2026-01-26factory_direct_fiwatching my heart rate#retatrutide · 2026-01-29area_percentstepping back down on purpose is a completely reasonable move and this channel should say so more often#dosing-titration · 2026-01-30nhs_pathway_nellif the current dose is still working, going up is spending headroom you might want later#dosing-titration · 2026-02-01logrotatesmaller steps here#retatrutide · 2026-02-03meniscus_melhow do you tell a plateau from just being at your set point#dosing-titration · 2026-02-11satiety_sigGI was about the same as tirzepatide for me, the difference was how fast it arrived#retatrutide · 2026-02-14split_shipmentanyone gone above 7.5 and what changed#retatrutide · 2026-02-15lisbon_lotthe purity spread across lots worries me more than the molecule does#retatrutide · 2026-02-15bac_water_billenergy expenditure isnt something i could feel, though my sleep tracker disagreed with me#retatrutide · 2026-03-06two_eight_cis TRIUMPH the phase 3 programme#retatrutide · 2026-03-08seizure_letterthere is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists#retatrutide · 2026-03-17declared_valuestepping in 1.7 increments instead of doubling is the only thing i would change if i started again#retatrutide · 2026-03-17electrolyte_eliappetite suppression at 5 was stronger than my tirzepatide experience at a comparable point#retatrutide · 2026-03-20taper_tessi escalate on symptoms. if the current dose is still doing something i stay on it#dosing-titration · 2026-03-27noct.titratewhats the half life like, is it weekly the same way#retatrutide · 2026-03-30ghk_giawhat does the room think about jumping a rung to catch up#dosing-titration · 2026-03-30unsolicited_dmquick one research use only is on every vial and i treat it as exactly that, nobody here is prescribing#retatrutide · 2026-03-31bea_reconstitutesslightly off topic but whats a sensible starting point, im seeing everything from 0.5 to 2#retatrutide · 2026-04-05mg_per_mli drifted from sunday to wednesday over a year and only noticed when i checked the log, ask me again in a month#dosing-titration · 2026-04-10quiet.hoursenergy expenditure isnt something i could feel, though my sleep tracker disagreed with me#retatrutide · 2026-04-13lisbon_lottriple agonist yeah#retatrutide · 2026-04-17thirty_min_waitresearch use only is on every vial and i treat it as exactly that, nobody here is prescribing#retatrutide · 2026-04-22coa_or_copemy resting heart rate is up about 3 bpm, did that settle for anyone#retatrutide · 2026-05-04VialBotarchive lookup: 5 heart-rate series logged in #retatrutide, mean reported rise +7 bpm, range +3 to +16. n is tiny, treat…#retatrutide · 2026-05-05u100_pathow do people square the research use only framing with logging their own use#retatrutide · 2026-05-10is_this_foreveri went up too fast, got a fortnight of nothing but nausea, and dropped back two steps, for what its worth#retatrutide · 2026-05-14is_this_foreverTRIUMPH is phase 3#retatrutide · 2026-05-14u100_pati went to the top of the ladder, felt no better than two rungs down, and came back. that is data for me and nobody else, i…#dosing-titration · 2026-05-15egfr_edwhats a sensible starting point, im seeing everything from 0.5 to 2#retatrutide · 2026-05-22reta_resting_hrGI was about the same as tirzepatide for me, the difference was how fast it arrived#retatrutide · 2026-05-22bea_reconstitutessmaller steps here#retatrutide · 2026-05-24area_percentlow and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom, ymmv#retatrutide · 2026-05-28underfill_umaslightly off topic but stepping in 0.25 increments instead of doubling is the only thing i would change if i started again#retatrutide · 2026-06-03gall_bladder_gavglucagon is the new bit#retatrutide · 2026-06-07fasting_insulinheld at 1.7 for 4 months and it never plateaued for me, which i cant explain, we shall see#retatrutide · 2026-06-07batch_banditnobody should read my log as a plan, im recording what i did and thats all it is#retatrutide · 2026-06-11tb500_tobiasanyone tracking blood pressure alongside the heart rate#retatrutide · 2026-06-15amsterdam_aliquottriple agonist yeah#retatrutide · 2026-06-23tansy_testscoming back to this i was wrong to call the heart rate a non issue last year, enough people logged it that i changed my mind#retatrutide · 2026-06-24nausea_windowslightly off topic but small steps are better than big ones and the only reason people take big ones is impatience#dosing-titration · 2026-06-26bolus_bosplit dosing has no trial behind it. people here do it and report on it, thats all#dosing-titration · 2026-06-28